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Wir haben hier eine gewisse Anzahl an Studien aufgelistet, die die Wirkungsmechanismen und die Effektivität der von uns verwendeten aktiven Wirkstoffe belegen. Gerne hätten wir ein paar der Studien komplett oder zumindest deren Zusammenfassungen zur Verfügung gestellt. Da jedoch die Rechte an den Publikationen den Verlagen obliegt, ist uns dies zum augenblicklichen Zeitpunkt leider nicht möglich.


Volek, J. et al. 2002.  L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 282: E474-E482.

Kraemer, W. et al. 2003.  The effects of L-carnitine L-tartrate supplementation of hormonal responses to resistance exercise and recovery. J Strength Cond. Res. 17(3): 455-462. 

Kraemer, W et al. 2006.  Androgenic responses to resistance exercise: effects of feeding and L-carnitine. Med Sci Sports Exerc. 38(7): July: 1288-1296. 

Spiering, B. et al. 2007.  Responses of Criterion Variables to different supplemental doses of L-Carnitine L-Tartrate. J Strength Cond. Res.  21(1): 259-264. 

Spiering, B. et. al.  2008.  Effects of L-Carnitine L-Tartrate Supplementation on Muscle Oxygenation Responses to Resistance Exercise.  J. Strength Cond. Res.  22(4):1130-1135. 

Volek, J. et al.  2008. Effects of Carnitine Supplementation on Flow-Mediated Dilation and Vascular Inflammatory Responses to a High-Fat Meal in healthy Young Adults.  Am. J. Cardiol. 102:1413-1417. 

Ho, J.Y. et al.  2010. L-Carnitine L-Tartrate supplementation favorably affects biochemical markers of recovery from physical exertion in middle-aged men and women.  Metabolism, in press



Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE); Constantin Dallasa, Alain Gerbib, Guillaume Tencac, Franck Juchauxc, François-Xavier Bernard

A polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL Xpur) acting as lipolytic agent in overweight peoples and improved inflammatory, glycemic and oxidative status; Constantin Dallas, Alain Gerbi, Yves Elbez, Philippe Caillard, Nicolas Zamaria and Maurice Cloarec



Svetol®, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volenteers with overweight problems; Dellalibera SSA O, Lemaira B., Lafay S. 

Green coffee extract Svetol® can manage weight: a review; Karine Nardon, Benoit Lemaire, Sophie Lafay; Berkem Développement, Marais Ouest, 24680 Gardonne, France AgroFood industry hi-tech, September/October 2007, Anno 18 – No. 5




Anderson, R.A. ; Bryden, N.A. ; Polansky, M.M. ; Gautschi, K. (1996). Dietary chromium effects on tissue chromium concentrations and chromium absorption in rats. The Journal of Trace Elements in Experimental Medicine ; 9 ; 11-15. 

Anderson, R.A. ; Cheng, N. ; Bryden, N.A. ; Polansky, M.M. ; Chi, J. ; Feng, J. (1997). Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes ; 46 ; 1786-1791.

Anderson, R.A. ; Polansky, M.M. ; Bryden, N.A. (2004). Stability and absorption of chromium and absorption of chromium histidinate complexes by humans. Biological Trace Element Research ; 101 ; 211-218.

Anton, S.D. ; Morrison, C.D. ; Cefalu, W.T. ; Martin, C.K. ; Coulon, S. ; Geiselman, P. ; Han, H. ; White, C.L. ; Williamson, D.A. (2008). Effects of chromium picolinate on food intake and satiety. Diabetes Technology and Therapeutics ; 10(5) ; 405-412.

Bahadori, B. ; Wallner, S. ; Hacker, C. ; Boes, U. ; Komorowski, J.R. ; Wascher, T.C. (1999). Effects of chromium picolinate on insulin levels and glucose control in obese patients with type-II diabetes mellitus. Diabetes ; 48 ; A349.

Cefalu, W.T. ; Bell-Farrow, A.D. ; Stegner, J. ; Wang, Z.Q. ; King, T. ; Morgan, T. ; Terry, J.G. (1999). Effect of chromium tripicolinate on insulin sensitivity in vivo. The Journal of Trace Elements in Experimental Medicine ; 12 ; 71-83.

Cheng, N. ; Zhu, X. ; Shi, H. ; Wu, W. ; Jiamin, C. ; Jianying, C. ; Anderson, R.A. (1999). Follow-up survey of people in China with type 2 diabetes mellitus consuming supplemental chromium. The Journal of Trace Elements in Experimental Medicine ; 12 ; 55-60.

DiSilvestro R.A. ; Dy, E. (2007). Comparison of acute absorption of commercially available chromium supplements. The Journal of Trace Elements in Medicine and Biology ; 21 ; 120-124.

Evans, G.W. (1989). The effect of chromium picolinate on insulin controlled parameters in humans. Int. J. Biosocial. Med. Res. ; 11 ; 163-180.

Feng, J ; Lin, D. ; Zheng, A. ; Cheng, N. (2002). Chromium picolinate reduces insulin requirement in people with type 2 diabetes mellitus. Diabetes ; 51 ; A469.

Ghosh, D. ; Bhattacharya, B. ; Mukherjee, B. ; Manna, B. ; Sinha, M. ; Chowdhury, J. ; Chowdhury, S. (2002). Role of chromium supplementation in Indians with type 2 diabetes mellitus. J. Nutr. Biochem. ; 13 ; 690-697.

Jovanovic-Peterson, L. ; Gutlerrez, M. ; Peterson, C.M. (1999). Chromium supplementation for women with gestational diabetes mellitus. The Journal of Trace Elements in Experimental Medicine ; 12 ; 91-97.

Kaats, G.R. ; Blum, K. ; Fisher, J.A. ; Adelman, J.A. (1998). Effects of chromium picolinate supplementation on body composition: a randomized, double-masked, placebo-controlled study. Current Therapeutic Research ; 57(10) ; 747-756.

Lucidi et al. (2005). Effect of chromium supplementation on insulin resistance and ovarian and menstrual cyclicity in women with polycystic ovary syndrome. Fertil. Steril. ; 84 ; 1755-1757.

Lydic, M.L. et al. (2006). Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome. Fertil. Steril. ; 86 ; 243-246.

Morris, B.W. ; Kouta, S. ; Robinson, R. ; MacNeil, S. ; Heller, S. (2000). Chromium supplementation improves insulin resistance in patients with type 2 diabetes mellitus. Diabet. Med. ; 17 ; 684-685.

Rabinovitz, H. ; Leibovitz, A. ; Madar, Z. ; Gabai, G. ; Habot, B. (2000). Blood glucose and lipid levels following chromium supplementation in diabetic elderly patients on a rehabilitation program. Gerontologist ; 40.

Ravina, A. ; Slezak, L. ; Rubal, A. ; Mirsky, N. (1995). Clinical use of the trace element chromium (III) in the treatment of diabetes mellitus. The Journal of Trace Elements in Experimental Medicine ; 8 ; 183-190.

Ravina, A. ; Slezak, L. ; Mirsky, N. ; Bryden, N.A. ; Anderson, R.A. (1999). Reversal of corticosteroid-induced diabetes mellitus with supplemental chromium. Diabet. Med. ; 16 ; 164-167.


Citrus aurantium: 

Ph. D. Dallsa Clouatre (2003): Users guide to weight-loss supplements: Learn how to sort through all the fads and supplements and successfully loss weight. Basic Health Publication; 1 edition (September 2003)

Preuss HG, DiFerdinando D, Bagchi M, Bagchi D. (2002): Citrus aurantium as a thermogenetic, weight-reduction replacement for ephedra: an overview. J Med. 2002; 33 (1-4): 247-64. Review.

Kim KW, Kim HD, Jung JS, Woo RS, Kim HS, Suh HW, Kim YH, Song DK. (2001): Characterization of antidepressant-like effects of p-synehrine stereoisomers. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jul; 364 (1): 21-6

Pathak B., Gougeon R. (1998): Thermic effect of citrus aurantium in obese subjects. McGill Nutrition and Food Science Center, Royal Victora Hospital

Hedrei P., Gougeon R. (1997): Thermogenetic effects of beta-sympathicomimetik compounds extracted from citrus aurantium in humans. McGill Nutrition and Food Science Center, Royal Victora Hospital

Song DK, Suh HW, Jung JS, Wie MB, Son KH, Kim YJ (1996): Antidepressant-like effect of p.synephrine in mouse models of immobility test. Neurosci Lett. 1996 Aug 23; 214 (2-3): 107-10




Andrew Scholey & Anastasia Ossoukhova & Lauren Owen & Alvin Ibarra & Andrew Pipingas & Kan He & Marc Roller & Con Stough (2010): Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study. Psychopharmacology (2010) 212:345–356 DOI 10.1007/s00213-010-1964-y




Proclaim: JH Kim, D Desor, YT Kim, WJ Yoon, KS Kim, JS Jun, KH Pyun and I Shim (29. November 2006): Efficacy of as1-casein hydrolysate on stress-related symptoms in women .

IGHD: Zara de Saint-Hilaire, Michaël Messaoudi, Didier Desor and Toshinori Kobayashi (2009): Effects of a Bovine Alpha S1-Casein Tryptic Hydrolysate (CTH) on Sleep Disorder in Japanese General Population.

Lanoir, D.; Canini, F.; Messaoudi, M.; Lefranc, C.; Demagny, B.; Martin, S. and Bourdon, L. (2002): Long term effects of a bovine milk alpha-S1 casein hydrolysate on healthy low and high stress responders. Stress, 5 (suppl.), 124.

Messaoudi, M; Lefranc-Millot, C.; Desor, D.; Demagny, B.; Bourdon, L. (2005): Effects of a tryptic hydrolysate from bovine milk alpha (S1)-casein on hemodynamic responses in healthy human volunteers facing successive mental and physical stress situations. Eur J Nutr. Mar; 44(2):128-32. Epub 2004 Nov2.

Kim, J.H.; Desor, D.; Kim, Y.T.; Yoon, W.J.; Kim, K.S.; Pyun, K.H. and Shim, I. (2006). Efficacy of α-S1- casein hydrolysate on stress-related symptoms in women. European Journal of Clinical Nutrition, 1-6.

Saint Hilaire, Z.; Messaoudin M.; Desorn D.; Kobayashi, T. (2008). Effects of a bovine αs1-casein tryptic hydrolysate (CTH) on sleep disorder in japanese general population. The Open Sleep Journal, 2009, 2, 26-32.




L. Velpandian, R. Jasuja, R.K., Bhardwaj, J. Jaiswal, S.K. Gupta (2001): Piperine in Food: Interference in the Pharmacokinetics of Phenytoin. European Journal of Drug Metabolism and Pharmacokinetics, 2001, Vol. 26, No. 4, pp. 241-248.

Jeremy J. Johnson, Minakshi Nihal, Imtiaz A. Siddiqui, Cameron O. Scarlett, Howard H. Bailey, Hasan Mukhtar, and Nihal Ahmad (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. Mol Nutr Food Res. 2011 August ; 55(8): 1169–1176. doi:10.1002/mnfr.201100117.

Vladimir Badmaev, M.D. Ph.D. and Muhammed Majeed, Ph.D.: Comparison of nutrient bioavailability when ingested alone and in combination with BIOPERINE® Research Report, Sabinsa Corporation





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